Studies and Trials

Scientific advancements and medical breakthroughs at the forefront of the evolving medical cannabis field


Studies
News

study

July 12, 2016

J Pain: Nabilone for the Treatment of Pain in Fibromyalgia

Journal of Pain: To our knowledge, this is the first randomized, controlled trial to assess the benefit of nabilone, a synthetic cannabinoid, on pain…

study

July 11, 2016

Cannabinoids for Neuropathic Pain

Current Pain and Headache Reports: This article reviews the history, development, study results, and future potential of non-smoked, oral, non-psycho…

study

July 11, 2016

Medical Marijuana and Chronic Pain: A Review of Basic Science and Clinical Evidence

Current Pain and Headache Reports: Cannabinoid compounds include phytocannabinoids, endocannabinoids, and synthetics. The two primary phytocannabin…

study

July 11, 2016

Cannabinoids in the Management of Difficult to Treat Pain

Journal of Therapeutics and Clinical Risk Management This article reviews recent research on cannabinoid pain mechanisms, as well as randomized clini…

study

July 11, 2016

Cannabinoids for the Treatment of Chronic Non-Cancer Pain: Updated Review of Randomized Controlled Trials

Journal of Neuroimmune Pharmacology: An updated systematic review of randomized controlled trials examining cannabinoids in the treatment of chronic…

study

July 11, 2016

Efficacy, Tolerability and Safety of a Cannabis-Based Medicine (Sativex) in the Treatment of Rheumatoid Arthritis

Oxford Journals - Rheumatology: Evidence from basic science and human trials suggests thatcannabis-based medicines (CBM) may have therapeutic potenti…

study

July 11, 2016

AAN: Cannabis in Painful HIV-Associated Sensory Neuropathy

American Academy of Neurology: To determine the effect of smoked cannabis on the neuropathic pain of HIV-associated sensory neuropathy and an experim…

study

July 11, 2016

J Pain: Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy

Journal of Pain: This small, short-term, placebo-controlled trial of inhaled cannabis demonstrated a dose-dependent reduction in diabetic peripheral…

study

July 11, 2016

J Pain: Cannabis for the Management of Pain: Assessment of Safety Study (COMPASS)

Journal of Pain: Cannabis is widely used as a self-management strategy by patients with a wide range ofsymptoms and diseases including chronic non-ca…

study

July 11, 2016

JPSM: Study of the Efficacy, Safety, and Tolerability of THC & CBD in Patients with Intractable Cancer-Related Pain

Journal of Pain and Symptom Management: A combination of THC and CBD extract was more efficacious than an extract of THC alone in a placebo-controlle…

study

July 7, 2016

JAMA: A Controlled Trial to Improve Care for Seriously III Hospitalized Patients

Journal of the American Medical Association: The study to understand rognoses and preferences for outcomes and risks of treatments Source: JAMA JAM…

study

July 7, 2016

Evidence for the Efficacy and Effectiveness of THC-CBD Oromucosal Spray for Patients with Multiple Sclerosis

Therapeutic Advances in Neurological Disorders: For a summary of the available data on this cannabinoid oromucosal spray for MS-related spasticity, s…

study

July 7, 2016

JNNP: Efficacy and Safety of Cannabinoid Oromucosal Spray for Multiple Sclerosis Spasticity

Journal of Neurology, Neurosurgery, & Psychiatry:This study describes the efficacy and safety of a cannabinoid oromucosal spray containing equal a…

study

July 7, 2016

JNNP: Cannabinoids in Multiple Sclerosis (CAMS) Study

Journal of Neurology, Neurosurgery, & Psychiatry: Effectiveness and long-term safety of cannabinoids in MS: 630 subjects with stable MS and muscl…

study

July 7, 2016

JNNP: Multiple Sclerosis and Extract of Cannabis: Results of the MUSEC Trial

Journal of Neurology, Neurosurgery, and Psychiatry: MS and Extract of Cannabis (MUSEC): Participants with stable MS were randomly assigned to receive…

study

July 7, 2016

Cannabinoids in the Management of Spasticity Associated with Multiple Sclerosis

Neuropsychiatric Disease and Treatment: This review article summarizes the current understanding of cannabinoids in the nervous system, as well as th…

study

July 7, 2016

AAN: Summary of Evidence-Based Guideline: Complementary and Alternative Medicine in Multiple Sclerosis

American Academy of Neurology: To develop evidence-based recommendations for complementary and alternative medicine (CAM) in multiple sclerosis (MS)…

study

July 7, 2016

GW Research: Antiepileptic Efficacy Study of Cannabidiol in Children and Young Adults With Dravet Syndrome

GW Research: Since 2013, a consortium of 10 epilepsy centers has been collecting prospective data on children and young adults with severe epilepsy w…

study

July 7, 2016

GW Research: A Study to Investigate the Efficacy and Safety of Cannabidiol as Adjunctive Treatment for Lennox-Gastaut Syndrome in Children and Adults

GW Research: Since 2013, a consortium of 10 epilepsy centers has been collecting prospective data on children and young adults with severe epilepsy w…

study

July 7, 2016

The Lancet Neurology: Cannabidiol in Patients with Treatment-Resistant Epilepsy

The Lancet Neurology: In December 2015, an open-label study of an oral cannabidiol (CBD) product (Epidiolex®) showed significantly reduced seizure fr…

study

July 7, 2016

Cannabidiol: Pharmacology and Potential Therapeutic Role in Epilepsy and Other Neuropsychiatric Disorders

Epilepsia: To present a summary of current scientific evidence about the cannabinoid, cannabidiol (CBD) with regards to their relevance to epilepsy a…

study

July 7, 2016

Cochrane Review: Cannabinoids for Epilepsy

Cochrane Review: Four randomized controlled trial reports that included a total of 48 patients, each of which used cannabidiol as the treatment agent…

study

July 7, 2016

Parental Reporting of Response to Oral Cannabis Extracts for Treatment of Refractory Epilepsy

Epilepsy & Behavior: In a 2015 survey of 75 parents whose children were treated with oral cannabis extracts in Colorado, the parents reported tha…

study

July 7, 2016

Report of a Parent Survey of Cannabidiol-Enriched Cannabis Use in Pediatric Treatment-Resistant Epilepsy

Epilepsy & Behavior: A 2013 survey of caregivers of 19 children with severe epilepsy who were receiving cannabidiol-enriched cannabis extracts in…

study

June 16, 2016

AAN: Efficacy and Safety of Medical Marijuana in Selected Neurologic Disorders

American Academy of Neurology:  "We performed a systematic review of medical marijuana (1948–November 2013) to address treatment of symptoms of multi…

study

June 16, 2016

NEJM: Cannabinoids in the Treatment of Epilepsy

The New England Journal of Medicine:  The pharmacologic and biochemical features of cannabinoids make them candidates for antiseizure medications. At…

study

June 16, 2016

JAMA: Importance of Accurate Labeling for Safe and Effective Use of Medical Cannabis Products

The Journal of the American Medical Association: As the use of cannabis (marijuana) for medical purposes has expanded, a variety of edible products f…